LUCA Science is pioneering a new class of mitochondrial therapy to restore cellular bioenergetics in dysfunctional or damaged cells and tissues.  

Our Mission　

Enabling functional mitochondria as therapeutic agents to restore energy for life.

Our Approach

In recent studies, mitochondria are recognized as an integrative hub coordinating immune and metabolic systems. Dysfunction in mitochondria from genetic mutation, environmental stress, or aging is associated with various diseases.

LUCA Science is developing an innovative platform of highly functional mitochondria using our proprietary iMIT technologies. By providing intact and functional mitochondria to the affected tissues, we could improve bioenergetics and normal functions could be restored. The use of mitochondria as a biopharmaceutical agent would be revolutionary for the treatment of many unmet medical needs.

Our Mitochondria

Life is only possible when the structures are provided with energy, but treatments to improve bioenergetics deficiency have not been addressed enough in modern medicine.

Mitochondria are the power plants in our cells that produce energy for our bodies. These small intracellular organelles are responsible for cellular aerobic respiration, the process which turns oxygen and nutrients into energy. Like any well-functioning machine, our tissues and organs are highly dependent on their energetic state to function properly.

Mitochondrial dysfunction caused by ischemia-reperfusion injuries such as cerebral infarction and myocardial infarction is one of the leading causes of death and disability around the world. Since the brain and heart tissues have high energy demands, they react very sensitively to oxygen deficiency. This sensitivity makes them most susceptible to reperfusion injuries when oxidative stress triggers cell necrosis due to mitochondrial damage. As a result, these tissues suffer irreversible functional and tissue injuries.

In our recent studies, we have been able to show that administering our proprietary functional and storable mitochondria to injured tissues could improve the bioenergetics and functions of such tissues.